Overview & Purpose

The central goal of the GDR "Approche Interdisciplinaire de l'Evolution Moléculaire" (AIEM) is to address fundamental questions in evolutionary biology by taking advantage of methods from quantitative statistics and applied mathematics as well as by discussing historical and philosophical perspectives of the field. To foster such cross-disciplinary dialog, we have organised this year’s annual meeting as two half days of contributed talks by members of the GDR and one full day on the dedicated topic of Molecular interactions in biology : describing, modeling and predicting their evolutionary properties for which we have invited two speakers that are developing work in this area. For the contributed talks we have chosen to prioritize young members of our community (PhD students and post-docs) to present their work, but ample space and time (and beer) will be made available to encourage interaction around posters for everyone to have an opportunity to participate.


Practical information

  • The venue of the meeting will be the Lilliad Learning Center of the campus “Cité Scientifique” in Villeneuve d’Ascq, that can be easily reached by metro Line 1.
  • Lunches and coffee breaks will be covered but evening diners will be at the charge of the participants themselves.

  • Lodging will be provided in double rooms for all participants at a nearby hotel on campus.



Link to Google Agenda

Wednesday 21st: contributed talks by members of the GDR

  • 13:30 -14:00 Coffee and Welcome Remarks

  • 14h-14h30 Mechanistic and evolutionary determinants of the impact of Neanderthal introgression on gene regulation - Martin Silvert

  • 14h30-15h Principal component analyses reveal the mosaic structure of modern rose genomes - Hélène Badouin

  • 15h-15h30 Y chromosome degeneration in Cannabis sativa - Djivan Prentout

  • 15h30-16h Exploring the Evolutionary History of the Malaria-Protective Haemoglobin ?S Mutation in African Agriculturalists and Rainforest Hunter-Gatherers - Guillaume Laval

  • 16h-16h20 COFFEE BREAK

  • 16h20-16h50 X- chromosome meiotic drive in Drosophila simulans: A QTL approach reveals the complex polygenic determinism of Paris drive suppression - Cécile Courret

  • 16h50-17h20 Catching de novo genes as they arise in natural populations - Eleonore Durand

  • 17h20-17h50 What if Schmalhausen and Waddington were right? Canalyzed genomes and evolution through stabilizing selection - Laurent Loison

  • 17h50-18h20 Conditions necessary for gene flow to produce a U-shaped Site Frequency Spectrum (SFS) - Nina Marchi

  • 18h20-19h POSTERS

    • The spatial Muller's ratchet: A model on expansion load - Foutel-Rodier Félix
    • Direct coupling prediction of amino acid using low-rank model - Shimagaki Kai
    • Detection of recent strong decline in populations by genomic approaches - Kerdoncuff Elise
    • Tempo et mode d'évolution des poissons cavernicoles - Policarpo Maxime
    • The nature of molecular adaptation: dissecting the contribution of radical and conservative amino acid substitutions to protein evolution in animals - Schneemann Hilde
    • What about PCP pathway in sponges ? - Vernale Amélie
  • 19h30 Diner in town

Thursday 22nd: Molecular interactions in biology : describing, modeling and predicting their evolutionary properties

  • 09h - 10h Keynote conference 1 Evolutionary dynamics of phenotypically structured populations in time-varying environments - Sepideh Mirrahimi

  • 10h-10h20 COFFEE BREAK

  • 10h20-10h50 The diverse challenges of computational protein docking - Marc Lensink

  • 10h50-11h20 A multi-scale coevolutionary approach to predict protein-protein interactions - Giancarlo Croce

  • 11h20-11h50 Inferring interaction partners from protein sequences - Anne-Florence Bitbol

  • 11h50-13h30 LUNCH

  • 13h30-14h30 Keynote conference 2. DNA double strand break repair in single E. coli cells - Meriem Elkharoui

  • 14h30-15h Multi-scale modeling of actin dynamics - Anne Van Gorp

  • 15h-15h30 Assessing correlated evolution by a likelihood approach – Abdelkader Behdenna

  • 15h30-15h50 COFFEE BREAK

  • 15h50-16h20 Coevolution analysis of amino-acids involved in immune evasion in Hepatitis B Virus – Elin Teppa

  • 16h20-16h50 Protein dynamics adaptation during evolution - Tristan Bitard

  • 16h50-17h20 Evolutionary dynamics of plasticity in a mechanistic gene-network model – Andréas Odorico

  • 17h20-17h50 Evolution of expression regulatory landscapes in vertebrates – Alexandre Laverré

  • 19:30 Diner in town

Friday 23rd: contributed talks by members of the GDR

  • 9h-9h30 The mechanistic basis of epistasis - Olivier Tenaillon

  • 9h30-10h The non-neutral impact of synonymous mutations at the protein and cellular levels - Ignacio Bravo

  • 10h-10h30 Regulatory interactions among non-coding RNAs in the evolution of the placenta - Anamaria Necsulea

  • 10h30-10h50 COFFEE BREAK

  • 10h50-11h20 Fixed-Size Determinantal Point Processes Sampling For Species Phylogeny - Diala Wehbe

  • 11h20-11h50 PhyloSofS: PHYLOgenies of Splicing isOForms Structures - Diego Javier Zea

  • 11h50-12h20 A Metropolis-Hastings Sampling of Subtrees in Graphs - Abdelrahman Eid

  • 12h20-12h50 The effect of recombination in Heliconus speciation - Camille Roux

  • 12h50 Sandwich bags provided



  • Registration is free but mandatory, through this website

  • Abstract for talks and posters have to be submitted through this website as well

  • Because the number of contributed talks will be limited, we will prioritize participants at early stages of their carrier, and ensure that the talks represent the diversity of groups that are participating to the GDR.

  • The number of participants is limited by the size of the conference room, which is capped at 100 seats.

  • Deadline for registration is october 19th, 2018




  • Université de Lille

  • Région Hauts de France

  • Chaire Véolia-Polytechnique

  • Labex CEMPI


  • CPER Climibio


Organizing and scientific committee

Sylvain Billiard

Viet Chi Tran

Camille Roux

Celine Poux

Xavier Vekemans

Guillaume Achaz

Vincent Castric

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